Nonsteroidal anti-inflammatory drugs and analgesics, adopted by a future mother, can affect the reproductive system of the fetus. This conclusion was made by British scientists based on the results of experiments on rats.
Of course, experiments have so far only been conducted on animals and rats. Nevertheless, the results of the experiment can not be ignored, since the reproductive system of these animals is very similar to the human.
During the experiment, two drugs were used in pregnant rats: Paracetamol and Indomethacin. They were given in large doses for 7 days. At the same time, they monitored the condition of their reproductive system. And it turned out that the negative effect of drugs is already on 1-4 days of drug therapy. Development of ovarian rats slowed. The born individuals had poor fertility. And moreover, the same reduced fertility was possessed by the pups born from them.
Scientists concluded that this is due to the influence of pain medications on the concentration of prostaglandins - hormones that are of great importance for the reproductive system.
Nevertheless, "Paracetamol" remains the drug of choice as an anesthetic and antipyretics in pregnancy at any time. And Indomethacin is a drug that can prevent premature birth in the second trimester.